CFD Simulations of Swirling Effects on the Performance of the Supersonic Nozzle for Micro-particle Delivery
نویسندگان
چکیده
A high-speed gas flow, generated by a miniature supersonic nozzle for microparticle acceleration, is investigated. In medical application, the powder formulation of drugs can be delivered into human skin or mucosal tissue for the treatment of a range of diseases. One of the main concerns for designing and evaluating such system is ensuing that microparticles are delivered into human skin with a controllable velocity range and spatial distribution. The initial experimental work suggested that the performance of the device strongly depends on the aerodynamics of the supersonic nozzles employed. In this paper, computational fluid dynamics is utilized to simulate a prototype device, with the aim of investigating the swirling flow in its supersonic nozzle. Swirling effects on the gas dynamics, vortex-shock interaction and performance are discussed. Key-Words: Nozzle, Numerical, Particle delivery, Simulation, Supersonic, Swirl
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